A dirty child is a healthy child

Guardian:

Researchers from the School of Medicine at the University of California found that being too clean could impair the skin's ability to heal. The San Diego-based team discovered that normal bacteria that live on the skin trigger a pathway that helps prevent inflammation when we get hurt.

These bugs dampen down overactive immune responses which can cause cuts and grazes to swell, or lead to rashes, according to research published in the online edition of Nature Medicine.

"These germs are actually good for us," said Professor Richard Gallo, who led the research.

[..] The findings bear out the "hygiene hypothesis", first proposed in the 1980s, which suggests that early childhood exposure to bugs might "prime" the immune system to prevent allergies. It has been used to explain why increasing numbers of children in developed countries, where antibacterial sprays and wipes are common, suffer from allergies such as hay fever and eczema. "The exciting implication of the work is that it provides a molecular basis to understand the hygiene hypothesis," said Prof Gallo. "This may help us to devise new therapeutic approaches for inflammatory skin diseases".

According to Allergy UK, rates of allergy trebled in the UK in the last decade, with one in three suffering.

The pressure group Parents Outloud, which campaigns to stop children being "mollycoddled" and "oversanitised" by health and safety regulations, welcomed the research. "Hopefully research like this will help parents realise that it's natural and healthy for children to get outdoors and get mucky and that it doesn't do their health any harm," said a spokeswoman, Margaret Morrissey.

I wasn't aware of this technical term for it, but I've held to a version of the hygiene hypothesis from a young age.

For instance I've long refused to routinely wash my hands before meals, but I know people who do so obsessively. Yet now I never get sick, and they do. Seems to me my immune system has been better trained.

I think not oversanitizing is to most pathogens what being vaccinated is to viruses: it gets you some exposure and gives your immune system an opportunity to build up resistance. Like running drills.